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Marketed Products
Retained Product Pipeline
-Fosphenytoin
-Melphalan
-Topiramate
Partner Product Pipeline
-Amiodarone
-Budesonide
-Clopidogrel

 


 

Topiramate in a Nutshell
 
  Markets
 
  • Topiramate is an orally administered drug marketed under the brand name of Topamax
  • 2.7 million patients using a range of therapeutic options
  • Total hospital costs in 2005 for epilepsy and convulsion patients was nearly $1.8 billion
  Product Advantages
 
  • Physicians prefer to use the same therapeutic agent utilized to treat patients on a chronic, prophylactic basis
  • Current formulation of Topamax is not optimal for acute use: patients may be unable to take oral medications and acute use is not currently approved for Topamax
  • We believe that Captisol-Enabled Topiramate IV will provide for faster onset of drug while providing administration to a wider audience
  Development Status
 
  • We are developing an IV formulation of topiramate in conjunction with the University of Minnesota to be used for the treatment of epilepsy
  • Pre-IND meeting with the FDA held in May 2008
Updated: May 29, 2008